Explore how cytokine pathways and endocytosis contribute to symptom burden in cancer patients undergoing chemotherapy.
Explore the fascinating biological connection between diabetes and cancer, including shared pathways, epidemiological evidence, and future treatment directions.
Discover how Tumor Necrosis Factor-alpha (TNF-α), a key immune molecule, directly promotes cancer by acting as a potent endogenous mutagen that corrupts DNA.
Explore chromosomal translocations - genetic rearrangements that drive cancer, cause genetic disorders, and their detection methods.
Explore how integrins transform from cellular tethers to cancer drivers in melanoma, and discover the revolutionary therapeutic approaches targeting these molecular systems.
Discover how the CHD1L gene hijacks cellular mechanisms to protect cancer cells from death, revealing new therapeutic possibilities.
Discover how Cyclooxygenase-2 (COX-2) drives malignant peripheral nerve sheath tumors and the promising therapeutic potential of COX-2 inhibitors in cancer treatment.
Discover how oxidized macrophage migration inhibitory factor (oxMIF) promotes tumor growth and the promising therapies targeting this protein isoform.
Exploring the connection between microRNA-21 and JAM-A protein in colorectal cancer progression and metastasis.
Groundbreaking research reveals how nanoparticles are actively transported into tumors by endothelial cells, challenging the long-held EPR effect theory in cancer nanomedicine.